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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
18.48
Human Site:
S533
Identified Species:
25.42
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S533
S
A
R
P
A
G
D
S
V
N
K
D
S
M
N
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S533
S
A
R
P
A
G
D
S
V
N
K
D
S
M
N
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S654
S
A
R
P
A
G
D
S
V
N
K
D
S
M
N
Dog
Lupus familis
XP_543550
1017
111618
T533
G
A
R
P
A
G
D
T
V
S
K
D
S
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
V533
A
R
P
T
G
E
S
V
S
K
D
S
M
N
A
Rat
Rattus norvegicus
NP_001129232
1015
111665
V533
A
R
P
T
G
E
P
V
S
K
D
S
M
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T533
T
A
A
S
I
K
P
T
D
D
A
A
S
K
D
Frog
Xenopus laevis
Q8QFR2
1013
112021
A533
T
K
P
A
E
E
T
A
N
K
E
S
G
N
V
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
T533
E
E
N
K
D
S
A
T
A
P
V
N
S
I
G
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
K533
P
P
P
S
S
A
A
K
V
L
E
D
N
K
D
Fruit Fly
Dros. melanogaster
O17468
1047
113397
L530
D
P
G
Q
S
N
E
L
L
R
T
P
R
L
E
Honey Bee
Apis mellifera
XP_001122939
838
91355
G379
Y
G
K
P
L
V
Q
G
G
C
T
V
M
E
A
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
P476
D
G
K
R
R
I
Q
P
V
F
C
G
T
T
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
N505
G
F
A
S
N
Q
D
N
I
P
N
H
S
Q
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
I533
R
D
L
S
G
K
E
I
V
C
R
N
P
D
L
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
T381
A
S
L
D
S
S
I
T
L
F
K
F
E
N
N
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
D531
S
T
K
P
V
Q
N
D
N
P
Q
T
I
L
D
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
0
0
N.A.
N.A.
13.3
0
6.6
13.3
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
N.A.
40
20
26.6
40
26.6
13.3
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
20
N.A.
6.6
13.3
13.3
P-Site Similarity:
N.A.
33.3
N.A.
26.6
46.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
30
12
6
24
6
12
6
6
0
6
6
0
0
18
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
6
0
0
0
0
% C
% Asp:
12
6
0
6
6
0
30
6
6
6
12
30
0
6
18
% D
% Glu:
6
6
0
0
6
18
12
0
0
0
12
0
6
6
6
% E
% Phe:
0
6
0
0
0
0
0
0
0
12
0
6
0
0
0
% F
% Gly:
12
12
6
0
18
24
0
6
6
0
0
6
6
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
0
0
6
6
6
6
6
0
0
0
6
6
0
% I
% Lys:
0
6
18
6
0
12
0
6
0
18
30
0
0
12
0
% K
% Leu:
0
0
12
0
6
0
0
6
12
6
0
0
0
12
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
18
18
0
% M
% Asn:
0
0
6
0
6
6
6
6
12
18
6
12
6
24
36
% N
% Pro:
6
12
24
36
0
0
12
6
0
18
0
6
6
0
0
% P
% Gln:
0
0
0
6
0
12
12
0
0
0
6
0
0
6
0
% Q
% Arg:
6
12
24
6
6
0
0
0
0
6
6
0
6
0
0
% R
% Ser:
24
6
0
24
18
12
6
18
12
6
0
18
42
0
0
% S
% Thr:
12
6
0
12
0
0
6
24
0
0
12
6
6
6
6
% T
% Val:
0
0
0
0
6
6
0
12
42
0
6
6
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _